Year: 2019
Type: dissertation
Abstract: It is well established that elderly individuals have increased difficulty sleeping at night combined with falling asleep and waking up earlier.Although these age-related declines in circadian output are clearly observable in activity recordings of laboratory animals, the underlying changes in molecular and neuronal activity remain unknown.The fruit fly, Drosophila melanogaster, has long been used as a model for studying the circadian system and for ageing research.In this thesis Drosophila was used as a model to study the effect of ageing on circadian and sleep behaviour.vii5.9.3 Knocking down slo in the clock has significant effect on circadian and sleep behaviour..................
Author: Jack Curran
Language: English
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2968119714