Work

Tetravalent Metal Ion Guests in Polyoxopalladate Chemistry: Synthesis and Anticancer Activity of [MO8Pd12(PO4)8]12– (M = SnIV, PbIV)

Year: 2019

Type: article

Abstract: The first two examples of polyoxopalladates(II) (POPs) containing tetravalent metal ion guests, [MO 8 Pd 12 (PO 4 ) 8 ] 12– (M = Sn IV, Pb IV ), have been prepared and structurally characterized in the solid state, solution, and gas phase. The interactions of the metal ion guests and the palladium-oxo shell were studied by theoretical calculations. The POPs were shown to possess anticancer activity by causing oxidative stress inducing caspase activation and consecutive apoptosis of leukemic cells.

Source: Inorganic Chemistry

DOI: 10.1021/acs.inorgchem.9b01129

Authors: Peng Yang, Tian Ma, Zhongling Lang, Sonja Misirlic-Dencic, Andjelka M. Isakovic, Attila Bényei, Mirjana B. Čolović, Ivanka Markovic, Danijela Z. Krstić, Josep M. Poblet, Zhengguo Lin, Ulrich Kortz

Institutions: Constructor University, Universitat Rovira i Virgili, University of Belgrade, University of Debrecen, Vinča Institute of Nuclear Sciences, Beijing Institute of Technology

Language: English

Topic: Polyoxometalates: Synthesis and Applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funders: European Cooperation in Science and Technology, Deutsche Forschungsgemeinschaft, National Natural Science Foundation of China, Generalitat de Catalunya, Institució Catalana de Recerca i Estudis Avançats, China Scholarship Council, Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja, Ministerio de Ciencia e Innovación

Awards: G1832270204, G2314108038, G2661569895, G3173079657, G4334055366, G485115087, G5245354606, G5734953729

OpenAlex ID: W2968690336

FWCI: 0.975

Cites: 44

Cited by: 23

Related to: 10