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Monoclonal Antibody Responses after Recombinant Hemagglutinin Vaccine versus Subunit Inactivated Influenza Virus Vaccine: a Comparative Study

Year: 2019

Type: article

Abstract: There are ongoing efforts to increase the efficacy of influenza vaccines and to promote production strategies that can rapidly respond to newly emerging viruses. It is important to understand if current alternative seasonal vaccines, such as Flublok and Flucelvax, that use alternate production strategies can induce protective influenza-specific antibodies and to evaluate what type of epitopes are targeted by distinct vaccine formulations.

Source: Journal of Virology

DOI: 10.1128/jvi.01150-19

Authors: Carole Henry, Anna-Karin E. Palm, Henry A. Utset, Min Huang, Irvin Y. Ho, Nai-Ying Zheng, Theresa Fitzgerald, Karlynn E. Neu, Yao-Qing Chen, Florian Krammer, John J. Treanor, Andrea J. Sant, David J. Topham, Patrick C. Wilson

Institutions: University of Chicago, University of Rochester Medicine, University of Rochester, Icahn School of Medicine at Mount Sinai

Language: English

Topic: Influenza Virus Research Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Awards: G103575219, G2419460583, G2577256337, G2935723395, G5148233484, University of Chicago Autoimmunity Center of Excellence, Interdisciplinary Training Program in Immunology, Vaccine and Infection Induced Immunity in the Young and Aged

OpenAlex ID: W2969257524

FWCI: 2.675

Cites: 48

Cited by: 25

Related to: 10