Get started
Work

The importance of prandial insulin bolus timing with hybrid closed‐loop systems

Year: 2019
Type: article
Abstract: Attainment of glycaemic targets for people with type 1 diabetes (T1D) is challenging and management of post-prandial hyperglycaemia is one key contributing factor. Due to delays in subcutaneous insulin absorption, administering rapid‐acting insulin boluses 15–20 minutes before a meal leads to approximately 30% reduction in post‐prandial glucose compared with boluses delivered immediately before the meal [1-3]. There is also a greater risk of post-prandial hypoglycaemia when people administer insulin boluses post-meal. People with T1D who routinely bolus rapid-acting insulin pre‐meal have better HbA1c values, according to large registry data [4].
DOI: 10.1111/dme.14116
Language: English
Field: Medicine
Open Access status: green
Funders: Leona M. and Harry B. Helmsley Charitable Trust, Wellcome Trust, National Institute for Health and Care Research, Cambridge University Hospitals, National Institute of Diabetes and Digestive and Kidney Diseases, NIHR Evaluation Trials and Studies Coordinating Centre
Awards: Institute of Metabolic Science., 24/7 closed-loop in older subjects with type 1 diabetes, G4903748289, G6525891988, Home testing of 24/7 closed-loop control in children and adolescents with type 1, Effect of closed loop insulin delivery from onset of diabetes in youth on progression of type 1 diabetes, G8585681489, G8589133502
OpenAlex ID: W2969524530
FWCI: 3.043
Cites: 5
Cited by: 29
Related to: 10