Fat Depots Distribution and Lipid Metabolism Markers in Obese Patients after Restrictive Bariatric Intervention
Year: 2019
Type: article
Abstract: The effect of restrictive bariatric surgery - laparoscopic sleeve gastrectomy on the parameters of lipid metabolism and the distribution of subcutaneous and visceral fat - was studied. The decrease in %EBW and the increase in %EWL have been persistent for 36 months after LSG, proving its restrictive effect. During the first year after LSG, there was a progressive weight loss, when overweight declined 4.1 times, and the percentage of lost weight reached 81.5±4.1%; The BMI at this time was characterized by values of 34.9±1.4 kg/m. Weight loss was accompanied by a decrease in the area of fat in the subcutaneous and visceral depot, as well as the positive dynamics of a inflammation marker - CRP. The reduction in visceral fat and CRP indicates a normalization of pro-inflammatory status as a result of LSG. Analysis of lipid metabolism parameters at various periods after LSG showed that the decrease in triglyceride concentration occurred quickly (as early as on the 7th day), and the cholesterol metabolism parameters — much slower — only 12 months after LSG, an increase in HDL cholesterol occurred. Excessive visceral fat in patients with morbid obesity is accompanied by impaired carbohydrate and lipid metabolism. As a result of the restrictive effect of LSG, there was also a positive metabolic effect. The positive dynamics of %EWL was followed by a decrease in VFA, SFA, as well as an improvement in lipid metabolism parameters and a decrease in cardiometabolic risk due to a reduction of TG/HDL.
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2969667272