Work

Material properties and osteoporosis

Year: 2019

Type: review

Abstract: The main clinical tool for the diagnosis and treatment of skeletal diseases such as osteoporosis is the determination of bone mineral density by dual x-ray absorptiometry. Although this outcome contributes to the determination of bone strength, the clinical evidence to date suggests that it does not correlate strongly with fracture incidence. The main reason for this discrepancy is the fact that several other bone properties, such as material properties, are not taken into account. This short review summarizes the reasons why material properties are important in the determination of bone strength and briefly discusses some of them as well as their influence on bone's mechanical performance.

Source: F1000Research

DOI: 10.12688/f1000research.18239.1

Authors: Eleftherios P. Paschalis, Klaus Klaushofer, Markus A. Hartmann

Institutions: Hanusch Hospital, Ludwig Boltzmann Institute of Osteology, Allgemeine Unfallversicherungsanstalt

Language: English

Topic: Bone health and osteoporosis research

Subfield: Orthopedics and Sports Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,350