Photoacoustic imaging of the uterine cervix to assess collagen and water content changes in murine pregnancy
Year: 2019
Type: article
Abstract: in murine cervical tissues that were collected in mid-pregnancy and at term. We report, for the first time, that our imaging approach provides information about the molecular changes in the cervix at different gestational ages. There was a strong correlation between the results of PA imaging and the histological assessment of the uterine cervix over the course of gestation. These findings suggest that PA imaging is a powerful method to assess the biochemical composition of the cervix and open avenues to non-invasively investigate the composition of this organ, which is essential for reproductive success.
Source: Biomedical Optics Express
Institutions: Wayne State University, National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Genomic Medicine, Universidad Nacional Autónoma de México, Florida International University, University of Michigan, Detroit Medical Center, Michigan State University
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,913
Funder: National Institutes of Health
Award: G3388402394
OpenAlex ID: W2969954258