Work

Perspective on Adenoviruses: Epidemiology, Pathogenicity, and Gene Therapy

Year: 2019

Type: review

Abstract: Human adenoviruses are large (150 MDa) doubled-stranded DNA viruses that cause respiratory infections. These viruses are particularly pathogenic in healthy and immune-compromised individuals, and currently, no adenovirus vaccine is available for the general public. The purpose of this review is to describe (i) the epidemiology and pathogenicity of human adenoviruses, (ii) the biological role of adenovirus vectors in gene therapy applications, and (iii) the potential role of exosomes in adenoviral infections.

Source: Biomedicines

DOI: 10.3390/biomedicines7030061

Authors: Brennetta J. Crenshaw, Leandra B. Jones, Courtnee’ R. Bell, Sanjay Kumar, Qiana L. Matthews

Institutions: Alabama State University, University of Alabama at Birmingham

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,013