Work

Brain delivery of a virus to block seizures helps mice get a silent NACHT

Year: 2019

Type: article

Abstract: For people with epilepsy, frontline treatment remains with anti-seizure drugs (ASDs), a group of over 20 different medicines available for this common, disabling brain disease. ASDs are effective in controlling seizures in approximately two-thirds of patients, but this leaves a very large number of people for whom seizures continue. This has devastating effects on quality of life and increases the risk for serious adverse events, including sudden unexplained death in epilepsy (SUDEP). In fact, the treatment gap is greater still.

Source: EBioMedicine

DOI: 10.1016/j.ebiom.2019.08.066

Author: David C. Henshall

Institution: Royal College of Surgeons in Ireland

Language: English

Topic: Epilepsy research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,500