Work

Advanced glycosylation end product promotes forkhead box O1 and inhibits Wnt pathway to suppress capacities of epidermal stem cells.

Year: 2016

Type: article

Abstract: < 0.01). Immunoprecipitation analysis showed that FOXO1 could compete with lymphoid enhancer binding factor 1 to interact with β-catenin, which might help to elucidate the mechanism of AGE repressing ESCs. This study helps to understand the mechanism of accumulated AGE in affecting ESC capacities, and provides potential therapeutic targets to meliorate diabetic wound healing.

Source: PubMed

Authors: Jie Zhu, Peng Wang, Zhimin Yu, Wei Lai, Yi Cao, Pinbo Huang, Qiaodong Xu, Menglei Yu, Junyao Xu, Zitong Huang, Bing Zeng

Institutions: Sun Yat-sen University, Sun Yat-sen Memorial Hospital, Guangzhou Medical University

Language: English

Topic: Advanced Glycation End Products research

Subfield: Clinical Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2970384482

FWCI: 1.022

Cites: 39

Cited by: 13

Related to: 10