Assessment of novel, non-invasive interventions for the prevention of foot ulceration in patients with diabetes and a mechanistic study of progenitor cells from diabetic patients
Year: 2018
Type: dissertation
Study design: Clinical Trial
Abstract: entitled -Assessment of Novel, Non-Invasive Interventions for the Prevention of Foot Ulceration in Patients with Diabetes and a Mechanistic Study of Progenitor Cells from Diabetic Patients, September 2017Diabetic foot ulceration (DFU) is a known major complication of diabetes mellitus which contributes to lower extremities amputation.This study aimed to investigate the use of interventional devices either as a preventative or therapeutic strategy to improve clinical management of this pathology, as well as investigating the impaired function of endothelial progenitor cells in the diabetic condition.The first element targeted plantar callus formation among diabetic neuropathic (NRP) patients through the use of a SurroSenseRx TM biofeedback device.Reducing foot pressure with improved walking strategy in the 6 months study in diabetic neuropathy patients (n=20) appeared to minimise the size of non-ulcerative plantar callus (p<0.05),potentially reducing future ulcer recurrence.The 2 nd study focused on the use of a Geko TM electrical stimulation device to enhance DFU healing in 24 patients.Wounds
Authors: Bin Hasan, Ahmad Najib
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2970422670