Correction: Establishment and characterization of a primary androgen‐responsive African‐American prostate cancer cell line, E006AA. Prostate 2004;60(2):145‐152
Year: 2019
Type: erratum
Abstract: New information has been obtained on the E006AA epithelial cell line which was characterized in the paper we published in the Prostate 60(2):141-152 (2004) as having originated from an African American prostate tumor line. We now believe that this cell line is a subclone of the 786-O renal adenocarcinoma line from a white male. The STR profile of the E006AA subclone E006AA-hT, available at the American Type Culture Collection (ATCC) site has STRs which match the profile of 786-O cells (also available at the ATCC site). The analyses presented in the 2004 article are original and accurate using the techniques and methodologies that were available at the time (eg, H&E staining, cell-type and prostate-specific marker, AR expression, RT_PCR, Tumorigenicity, Karyotype, etc). We had no reason to doubt that the line we cultured did not originate from an African American prostate tumor. We now believe it may have been contaminated in its early passages with the 786-0 cell line before it was cryopreserved, as 786-0 cells were also studied in the lab from which this line originated. We urge ATCC to cease advertising this cell line, E006AA-hT, as originating from African American prostate cancer tissue. We would also like to apologize for the confusion, costs, and delays in research this mistake may have caused other researchers; and we thank the researchers who brought this error to our attention. Shahriar Koochekpour, MD PhD Assistant Professor of Urology School of Medicine Louisiana State University Health Sciences Center 533 Bolivar Street, CSRB 4–17 New Orleans, LA 70112 Phone: (504) 568–7261 Fax: (504) 568–6888 [email protected] Adrienne Katner, D. Env., M.S. Assistant Professor of Environmental and Occupational Health Sciences School of Public Health Louisiana State University Health Sciences Center 2020 Gravier Street, 3rd Floor New Orleans, LA 70112 Phone: 504–568–5942 Fax: 504–568–5701 [email protected]
Source: The Prostate
DOI: 10.1002/pros.23800
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2970877633