Work

The Host Immune System Facilitates Disseminated Staphylococcus aureus Disease Due to Phagocytic Attraction to Candida albicans during Coinfection: a Case of Bait and Switch

Year: 2019

Type: article

Abstract: Invasive Staphylococcus aureus infections account for 15 to 50% of fatal bloodstream infections annually. These disseminated infections often arise without a defined portal of entry into the host but cause high rates of mortality. The fungus Candida albicans and the Gram-positive bacterium S. aureus can form polymicrobial biofilms on epithelial tissue, facilitated by the C. albicans adhesin encoded by ALS3 .

Source: Infection and Immunity

DOI: 10.1128/iai.00137-19

Authors: Devon L. Allison, Nina Scheres, Hubertine M. E. Willems, Carolien S. Bode, Bastiaan P. Krom, Mark E. Shirtliff

Institutions: University of Maryland, Baltimore, Academic Center for Dentistry Amsterdam, Vrije Universiteit Amsterdam, University of Amsterdam, University of Tennessee Health Science Center

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2971111781

FWCI: 2.504

Cites: 81

Cited by: 34

Related to: 10