Chiral Nitroarenes as Enantioselective Single-Electron-Transfer Oxidants for Carbene-Catalyzed Radical Reactions
Year: 2019
Type: article
Abstract: A new class of chiral oxidants is developed. These readily accessible oxidants contain a nitro group for oxidation and a chiral sulfonamide moiety for stereoselectivity control. The chiral information from the oxidants can effectively transfer to the substrates in carbene-catalyzed β-hydroxylation of enals via single-electron-transfer radical processes. We expect these oxidants to find unique applications in other asymmetric oxidations and oxygen-atom-transferring reactions.
Source: Organic Letters
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
Funders: National Research Foundation, Agency for Science, Technology and Research, National Research Foundation Singapore, Ministry of Education - Singapore, Nanyang Technological University, National Natural Science Foundation of China, Ministry of Science and Technology of the People's Republic of China, Guizhou University, Guizhou Science and Technology Department, Ministry of Education, India
OpenAlex ID: W2971871064