Year: 2019
Type: article
Study design: Case Report
Abstract: An 18-year-old man with hemoglobin SS-type sickle cell disease presented with acute onset of headaches and horizontal double vision. On examination, he was noted to have a right cranial nerve VI (abducens) palsy. The following day, he also developed an ipsilateral cranial nerve VII (facial) palsy. Neuroimaging was consistent with bony infarction of his clivus secondary to his sickle cell disease and inflammation of the adjacent dura (figure). His presentation and imaging findings are suggestive of transient inflammation of cranial nerves VI and VII as they passed in proximity to the peri-infarct inflammation along the skull base. He received apheresis for elevated sickle hemoglobin levels, and his symptoms resolved within 1 week. His repeat imaging showed resolution of the areas of inflammation and evolution of his bony infarct. His most recent evaluation by neurology at 2 years follow-up was unremarkable, and his symptoms have not recurred.
Source: Neurology
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2971878875