Work

Measuring changes in bioavailability of artemisinin

Year: 2015
Type: article
Abstract: Artemisinin, a potent antimalarial found in Artemisia annua, is currently used in combination with other antimalarial drugs (ACTs), mainly against Plasmodium parasites. Ingestion of A. annua dried leaves is more efficacious than ACT, possibly due to increased bioavailability of artemisinin. This project used a Caco-2 intestinal model to perform experiments showing the effects of specific phytochemicals on artemisinin transport. Artemisinin transport across Caco-2 monolayers varied with artemisinin concentration.
Source: Digital WPI
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: green
OpenAlex ID: W2971883354
FWCI:
Cites: 100
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Related to: 10