Work

CRISPR DNA base editors with reduced RNA off-target and self-editing activities

Year: 2019

Type: article

Source: Nature Biotechnology

DOI: 10.1038/s41587-019-0236-6

Authors: Julian Grünewald, Ronghao Zhou, Sowmya Iyer, Caleb A. Lareau, Sara P. Garcia, Martin J. Aryee, J. Keith Joung

Institutions: Harvard University, Massachusetts General Hospital, Center for Computational and Integrative Biology, Massachusetts General Hospital

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: U.S. Department of Defense, U.S. Department of Health and Human Services, Deutsche Forschungsgemeinschaft, Defense Advanced Research Projects Agency, National Human Genome Research Institute, National Institute of General Medical Sciences

Awards: G2196766716, THE PURPOSE OF THIS COOPERATIVE AGREEMENT IS TO FUND RESEARCH IN SUPPORT OF BTO IN THE AMOUNT OF 987,271 ON CONTRACT HR0011-17-2-0042., G4175877162, G5052434461, Evolution, Optimization, and Application of Genome Editing Technologies, G6855349143

OpenAlex ID: W2971914211

FWCI: 13.6

Cites: 24

Cited by: 335

Related to: 10