The Effect of Ethnicity on the Incidence of Postoperative Nausea and Vomiting in Moderate to High Risk Patients Undergoing General Anesthesia in South Africa: a Controlled Observational Study.
Year: 2017
Type: article
Study design: Observational Study
Abstract: BACKGROUND: We conducted this prospective controlled observational study to compare the effect of ethnicity on the risk of postoperative nausea and vomiting (PONV) between moderate to high-risk African and non-African patients undergoing general anesthesia. METHODS: Using Apfel score risk factors and predicted length of surgery (>30 minutes), 89 moderate to high risk patients undergoing general anesthesia were recruited in a university hospital between March 2009 and November 2010. Thirty patients in the non-African group and 59 patients in the African group were allocated using an ethnicity self identification questionnaire. Intraoperative anesthesia was standardized. PONV was assessed at 0 minutes, 15 minutes, 90 minutes, 180 minutes, and 24 hours. Generalized linear mixed effects models was used to determine the effect of ethnicity on PONV. RESULTS: = 0.055). Non-Africans had a 25 times higher reported nausea incidence than Africans over 24 hours. CONCLUSION: The incidence of PONV in non-Africans is significantly higher than in Africans. Non-African ethnicity is an independent risk factor for PONV. Current risk prediction models may be limited in multi-ethnic populations and further investigations are warranted to examine ethnicity as a risk factor.
Source: PubMed
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2972313868