Work

Water Networks Can Determine the Affinity of Ligand Binding to Proteins

Year: 2019

Type: article

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.9b06275

Authors: John F. Darby, Adam P. Hopkins, Seishi Shimizu, Shirley M. Roberts, James A. Brannigan, Johan P. Turkenburg, Gavin H. Thomas, Roderick E. Hubbard, Marcus Fischer

Institutions: University of York, Demuris (United Kingdom), Vernalis (R&D) Limited (United Kingdom), St. Jude Children's Research Hospital

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: Wellcome Trust, American Lebanese Syrian Associated Charities, European Synchrotron Radiation Facility, Biotechnology and Biological Sciences Research Council

OpenAlex ID: W2972491973

FWCI: 4.51

Cites: 54

Cited by: 150

Related to: 10