Association of Left Ventricular Ejection Fraction with Mortality and Hospitalization in an Unselected Echocardiographic Cohort of both Ambulatory and Hospitalized Patients
Year: 2019
Type: dissertation
Study design: Observational Study
Abstract: The prognostic impact of left ventricular ejection fraction (LVEF) in a broad range of patients, including those hospitalized for cardiac or non-cardiac reasons and unselected ambulatory patients has not been fully evaluated. Echocardiography is the most commonly used imaging modality used to assess LVEF given its versatility and availability, however it does have limitations in accuracy. We sought to examine the association between an echocardiographic-derived LVEF and risk of all-cause mortality, cardiovascular mortality and heart failure hospitalization in an unselected consecutive cohort of patients. We performed a retrospective cohort study of patients who underwent echocardiography in three large-scale tertiary healthcare systems in Ontario, Canada between 2007 and 2013 using linked administrative databases. We found that an echocardiographic-derived LVEF was able to stratify risk of multiple outcomes across a diverse spectrum of patient profiles encountered in everyday clinical practice in both ambulatory and hospitalized patients, including those admitted for non-cardiac reasons.
Source: TSpace (University of Toronto)
Author: Paul Angaran
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2972867274