Work

Pharmacokinetics and Dialytic Clearance of Isavuconazole during In Vitro and In Vivo Continuous Renal Replacement Therapy

Year: 2019

Type: article

Abstract: 4.85±3.79 L/h, and AUC 54.01±20.98 mg ⋅ h/L. Transmembrane clearance represented just 0.7% of the total isavuconazole clearance. These data suggest that isavuconazole is not readily removed by CRRT and no dose adjustments are necessary.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.01085-19

Authors: M. Biagi, D. Butler, X. Tan, S. Qasmieh, K. Tejani, S. Patel, R. M. Rivosecchi, M. H. Nguyen, C. J. Clancy, R. K. Shields, E. Wenzler

Institutions: University of Illinois Chicago, University of Illinois Hospital & Health Sciences System, University of Pittsburgh Medical Center, University of Pittsburgh

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases

Awards: Caspofungin pharmacokinetics-pharmacodynamics during intra-adbominal candidiasis, Characterization and suppression of resistance to new CRE agents

OpenAlex ID: W2973610239

FWCI: 1.342

Cites: 26

Cited by: 18

Related to: 10