Work

Galectin-8 in the onset of the immune response and inflammation

Year: 2019

Type: article

Abstract: Galectins (Gals), a family of mammalian lectins, have emerged as key regulators of the immune response, being implicated in several physiologic and pathologic conditions. Lately, there is increasing data regarding the participation of Galectin-8 (Gal-8) in both the adaptive and innate immune responses, as well as its high expression in inflammatory disorders. Here, we focus on the pro- and anti-inflammatory properties of Gal-8 and discuss the potential use of this lectin in order to shape the immune response, according to the context.

Source: Glycobiology

DOI: 10.1093/glycob/cwz077

Authors: María V Tribulatti, Julieta Carabelli, Cecilia A Prato, Oscar Campetella

Institutions: Consejo Nacional de Investigaciones Científicas y Técnicas, National University of General San Martín

Language: English

Topic: Galectins and Cancer Biology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Agencia Nacional de Promoción Científica y Tecnológica