Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass
Year: 2019
Type: article
Source: Bone
Authors: Kevin A. Maupin, Evan R. Himes, Artur P. Plett, Hui Lin Chua, Pratibha Singh, Joydeep Ghosh, Safa F. Mohamad, Irushi Abeysekera, Alexa Fisher, Carol Sampson, Jung-Min Hong, Paul Childress, Marta Alvarez, Edward F. Srour, Angela Bruzzaniti, Louis M. Pelus, Christie M. Orschell, Melissa A. Kacena
Institutions: Indiana University School of Medicine, Indiana University
Language: English
Topic: Bone Metabolism and Diseases
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Funders: Indiana Clinical and Translational Sciences Institute, National Institutes of Health, National Institute on Aging, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Center for Research Resources, National Center for Advancing Translational Sciences
Awards: G1516779377, Regulation of Hematopoietic Cell Production, A megakaryocyte/PGE2/osteoblast triad in the normal and aged niche, Indiana Clinical and Translational Science Institute (UL1), Indiana Clinical and Translational Sciences Institute, Indiana Clinical and Translational Science Institute (UL1), G798517211, Regulation of Osteoblast Function by Megakaryocytes: Key Signaling Proteins, Comprehensive Musculoskeletal Training Program
OpenAlex ID: W2959730785