Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma
Year: 2019
Type: article
Study design: Observational Study
Source: CHEST Journal
Authors: Priyadarshini Kachroo, Julian Hecker, Bo L. Chawes, Tarunveer S. Ahluwalia, Michael H. Cho, Dandi Qiao, Rachel S. Kelly, Su H. Chu, Yamini V. Virkud, Mengna Huang, Kathleen C. Barnes, Esteban G. Burchard, Celeste Eng, Donglei Hu, Juan C. Celedón, Michelle Daya, Albert M. Levin, Hongsheng Gui, L. Keoki Williams, Erick Forno, Angel C.Y. Mak, Lydiana Avila, Manuel E. Soto-Quiros, Michelle M. Cloutier, Edna Acosta-Pérez, Glorisa Canino, Klaus Bønnelykke, Hans Bisgaard, Benjamin A. Raby, Christoph Lange, Scott T. Weiss, Jessica A. Lasky-Su, Namiko Abe, Goncalo Abecasis, Christine Albert, Nicholette (Nichole) Palmer Allred, Laura Almasy, Alvaro Alonso, Seth Ament, Peter Anderson, Pramod Anugu, Deborah Applebaum-Bowden, Dan Arking, Donna K. Arnett, Allison Ashley-Koch, Stella Aslibekyan, Tim Assimes, Paul Auer, Dimitrios Avramopoulos, John Barnard, Kathleen Barnes, R. Graham Barr, Emily Barron-Casella, Terri Beaty, Diane Becker, Lewis Becker, Rebecca Beer, Ferdouse Begum, Amber Beitelshees, Emelia Benjamin, Marcos Bezerra, Larry Bielak, Joshua Bis, Thomas Blackwell, John Blangero, Eric Boerwinkle, Ingrid Borecki, Russell Bowler, Jennifer Brody, Ulrich Broeckel, Jai Broome, Karen Bunting, Esteban Burchard, Jonathan Cardwell, Cara Carty, Richard Casaburi, James Casella, Mark Chaffin, Christy Chang, Daniel Chasman, Sameer Chavan, Bo-Juen Chen, Wei-Min Chen, Yii-Der Ida Chen, Michael H. Cho, Seung Hoan Choi, Lee-Ming Chuang, Mina Chung, Elaine Cornell, Adolfo Correa, Carolyn Crandall, James Crapo, L. Adrienne Cupples, Joanne Curran, Jeffrey Curtis, Brian Custer, Coleen Damcott, Dawood Darbar, Sayantan Das, Sean David, Colleen Davis, Michelle Daya, Mariza de Andrade, Michael DeBaun, Ranjan Deka, Dawn DeMeo, Scott Devine, Ron Do, Qing Duan, Ravi Duggirala, Peter Durda, Susan Dutcher, Charles Eaton, Lynette Ekunwe, Patrick Ellinor, Leslie Emery, Charles Farber, Leanna Farnam, Tasha Fingerlin, Matthew Flickinger, Myriam Fornage, Nora Franceschini, Mao Fu, Stephanie M. Fullerton, Lucinda Fulton, Stacey Gabriel, Weiniu Gan, Yan Gao, Margery Gass, Bruce Gelb, Xiaoqi (Priscilla) Geng, Soren Germer, Chris Gignoux, Mark Gladwin, David Glahn, Stephanie Gogarten, Da-Wei Gong, Harald Goring, C. Charles Gu, Yue Guan, Xiuqing Guo, Jeff Haessler, Michael Hall, Daniel Harris, Nicola Hawley, Jiang He, Ben Heavner, Susan Heckbert, Ryan Hernandez, David Herrington, Craig Hersh, Bertha Hidalgo, James Hixson, John Hokanson, Kramer Holly, Elliott Hong, Karin Hoth, Chao (Agnes) Hsiung, Haley Huston, Chii Min Hwu, Marguerite Ryan Irvin, Rebecca Jackson, Deepti Jain, Cashell Jaquish, Min A. Jhun, Jill Johnsen, Andrew Johnson, Craig Johnson, Rich Johnston, Kimberly Jones, Priyadarshini Kachroo, Hyun Min Kang, Robert Kaplan, Sharon Kardia, Sekar Kathiresan, Laura Kaufman, Shannon Kelly, Eimear Kenny, Michael Kessler, Alyna Khan, Greg Kinney, Barbara Konkle, Charles Kooperberg, Stephanie Krauter, Christoph Lange, Ethan Lange, Leslie Lange, Cathy Laurie, Cecelia Laurie, Meryl LeBoff, Seunggeun Shawn Lee, Wen-Jane Lee, Jonathon LeFaive, David Levine, Dan Levy, Joshua Lewis, Yun Li, Honghuang Lin, Keng Han Lin, Simin Liu, Yongmei Liu, Ruth Loos, Steven Lubitz, Kathryn Lunetta, James Luo, Michael Mahaney, Barry Make, Ani Manichaikul, JoAnn Manson, Lauren Margolin, Lisa Martin, Susan Mathai, Rasika Mathias, Patrick McArdle, Merry-Lynn McDonald, Sean McFarland, Stephen McGarvey, Hao Mei, Deborah A. Meyers, Julie Mikulla, Nancy Min, Mollie Minear, Ryan L. Minster, Braxton Mitchell, May E. Montasser, Solomon Musani, Stanford Mwasongwe, Josyf C. Mychaleckyj, Girish Nadkarni, Rakhi Naik, Pradeep Natarajan, Sergei Nekhai, Deborah Nickerson, Kari North, Jeff O'Connell, Tim O'Connor, Heather Ochs-Balcom, James Pankow, George Papanicolaou, Margaret Parker, Afshin Parsa, Sara Penchev, Juan Manuel Peralta, Marco Perez, James Perry, Ulrike Peters, Patricia Peyser, Lawrence S. Phillips, Sam Phillips, Toni Pollin, Wendy Post, Julia Powers Becker, Meher Preethi Boorgula, Michael Preuss, Dmitry Prokopenko, Bruce Psaty, Pankaj Qasba, Dandi Qiao, Zhaohui Qin, Nicholas Rafaels, Laura Raffield, Vasan Ramachandran, D.C. Rao, Laura Rasmussen-Torvik, Aakrosh Ratan, Susan Redline, Robert Reed, Elizabeth Regan, Alex Reiner, Ken Rice, Stephen Rich, Dan Roden, Carolina Roselli, Jerome Rotter, Ingo Ruczinski, Pamela Russell, Sarah Ruuska, Kathleen Ryan, Phuwanat Sakornsakolpat, Shabnam Salimi, Steven Salzberg, Kevin Sandow, Vijay Sankaran, Christopher Scheller, Ellen Schmidt, Karen Schwander, David Schwartz, Frank Sciurba, Christine Seidman, Jonathan Seidman, Vivien Sheehan, Amol Shetty, Aniket Shetty, Wayne Hui-Heng Sheu, M. Benjamin Shoemaker, Brian Silver, Edwin Silverman, Jennifer Smith, Josh Smith, Nicholas Smith, Tanja Smith, Sylvia Smoller, Beverly Snively, Tamar Sofer, Nona Sotoodehnia, Adrienne Stilp, Elizabeth Streeten, Yun Ju Sung, Jessica Su-Lasky, Jody Sylvia, Adam Szpiro, Carole Sztalryd, Daniel Taliun, Hua Tang, Margaret Taub, Kent Taylor, Simeon Taylor, Marilyn Telen, Timothy A. Thornton, Lesley Tinker, David Tirschwell, Hemant Tiwari, Russell Tracy, Michael Tsai, Dhananjay Vaidya, Peter VandeHaar, Scott Vrieze, Tarik Walker, Robert Wallace, Avram Walts, Emily Wan, Fei Fei Wang, Karol Watson, Daniel E. Weeks, Bruce Weir, Scott Weiss, Lu-Chen Weng, Cristen Willer, Kayleen Williams, L. Keoki Williams, Carla Wilson, James Wilson, Quenna Wong, Huichun Xu, Lisa Yanek, Ivana Yang, Rongze Yang, Norann Zaghloul, Maryam Zekavat, Yingze Zhang, Snow Xueyan Zhao, Wei Zhao, Xiuwen Zheng, Degui Zhi, Xiang Zhou, Michael Zody, Sebastian Zoellner
Institutions: Brigham and Women's Hospital, Harvard University, University of Copenhagen, Gentofte Hospital, Copenhagen Prospective Studies on Asthma in Childhood, Massachusetts General Hospital, University of Colorado Anschutz, University of California, San Francisco, University of Pittsburgh, Children's Hospital of Pittsburgh, Henry Ford Health, Henry Ford Hospital, Hospital Nacional de Niños, University of Connecticut, UConn Health, University of Puerto Rico System, Boston Children's Hospital
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: U.S. Department of Defense, Mayo Clinic, AstraZeneca, GlaxoSmithKline, Sanofi, Tobacco-Related Disease Research Program, Brigham and Women's Hospital, Harvard School of Public Health, Massachusetts General Hospital, Yale University, Stanford University, North Carolina GlaxoSmithKline Foundation, Fred Hutchinson Cancer Research Center, Brown University, Columbia University, Duke University, Vanderbilt University, Harvard Medical School, University of North Carolina, Center for HIV/AIDS Educational Studies and Training, Hunter College, University of Pennsylvania, Emory University, University of Mississippi, Northwestern University, Pharmavite, Sandler Foundation, George Washington University, Boston University, Harvard University, University of Minnesota, Washington University in St. Louis, University of Michigan, Icahn School of Medicine at Mount Sinai, Cleveland Clinic, Strategiske Forskningsråd, University of Kentucky, University of Washington, Tulane University, Johns Hopkins University, University of Arizona, Baylor College of Medicine, University of Pittsburgh, University of Cincinnati, University of Virginia, University of Maryland, University of Iowa, American Asthma Foundation, University of Alabama, Howard University, Broad Institute, University of Texas Rio Grande Valley, Steno Diabetes Center Copenhagen, Lundbeckfonden, National Health Research Institutes, Danmarks Frie Forskningsfond, National Taiwan University, Kaohsiung Veterans General Hospital, H. Lundbeck A/S, National Institutes of Health, Genentech, University of California, Los Angeles, Albert Einstein College of Medicine, Yeshiva University, University of California, San Francisco, University at Buffalo, School of Medicine, Diabetes Research Center, University of Washington, University of Illinois at Chicago, University of Colorado Denver, Sanofi Pasteur, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Environmental Health Sciences, National Institute on Minority Health and Health Disparities
Awards: G1047949195, G1117976624, G1268573537, G1278681517, G1314613728, G1365915403, G141679577, G1678129981, G1679034992, G1739380281, G1809386597, G2040153736, G2189466114, Addressing disparities in chronic disease with a teen and young adult focus, G2282975390, G232264632, G2706449977, G2989046130, G3084499258, G3164151482, G3208052949, G324457968, G3296697868, Network-based Methods for Understanding Genetic Determinants and Epistasis in COPD, Poly-omic Study of Asthma Exacerbations in Diverse Populations, THE GENETIC EPIDEMIOLOGY OF ASTHMA IN COSTA RICA, G3977087618, G4086346382, G4119534169, G4183848059, G4486308096, G457392980, G4574420337, G4814476484, G4905463976, SF BUILD: Enabling full representation in science, G5272449015, Genetic Control of Airway Epithelium Gene Expression in Childhood Asthmatics, G579062127, G5850682332, G6307937119, Multi-Omic Endotyping of Asthma, G6460128660, G6703504239, G6707346057, G6725322507, G674653917, G7307112236, Deciphering the genetic mechanisms of atrial fibrillation, Genes, air pollution, and asthma severity in minority children, METABOLOMICS OF LEAD EXPOSURE AND ITS ROLE IN RESPIRATORY DISEASE, G7807399823, G784204608, G8008018803, G82491071, G8288748655, Studies of Rare Genetic Variation in the Isolated Population of Sardinia, G8921073602, G9000012587, G9000025080, G9000031130, G9000032667, G9000045720, G9000088078, G9000104403, G9000123620, G9000143814, G9000161611, G9000227757, G9000291987, G9000324557
OpenAlex ID: W2976705022