Work

The Two SH2 Domains of SHP-2 Bridge Two PD-1 Molecules Resulting in SHP-2 Activation and PD-1-Mediated Inhibition

Year: 2018

Type: conference-abstract

Source: Blood

DOI: 10.1182/blood-2018-99-117486

Authors: Nikolaos Patsoukis, Jonathan Duke-Cohan, Apoorvi Chaudhri, Eunyoung Park, Anders Berg, Gordon J Freeman, Michael Eck, Vassiliki A Boussiotis

Institutions: Beth Israel Deaconess Medical Center, Harvard University, Dana-Farber Cancer Institute

Language: English

Topic: Protein Tyrosine Phosphatases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2977549282

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