Year: 2016
Type: article
Abstract: This account describes the historical development of the coupling of ,-unsaturated Fischer carbene complexes and o-alkynylbenzaldehydes, which directly affords hydrophenanthrene ring systems in a process where each reactant contributes five carbons to the newly-formed bicyclo[4.4.0]decane ring system.The process has been termed net [5+5] cycloaddition.Use of the reaction to produce various medicinally important natural products and/or their parent ring systems is discussed.
Source: ARKIVOC
Authors: James W. Herndon, Bishnu Dhakal
Institution: New Mexico State University
Language: English
Topic: Catalytic Alkyne Reactions
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W2978803948