Long noncoding RNAs: a new regulatory code in osteoarthritis.
Year: 2017
Type: article
Abstract: It is reported that long noncoding RNAs (lncRNAs) were expressed aberrantly in cartilage of osteoarthritis (OA). Current evidence indicates that lncRNAs not only serve as positive or negative regulators of OA, but also crosstalk with multiple potential targets to impact on the critical events in OA process. This review summarized the lncRNAs identified in OA to date, discussed their influence on the survival of chondrocytes and synoviocytes, arthritis-associated factors, and angiogenesis, and indicated the potential in diagnosis, therapy, and prognosis.
Source: Europe PMC (PubMed Central)
Authors: Xiao Cen, Xin-Qi Huang, Wen-Tian Sun, Qing Liu, Jun Liu
Institutions: Sichuan University, State Key Laboratory of Oral Diseases
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2978968209