Work

Vancomycin resistant Staphylococcus aureus infections: A review of case updating and clinical features

Year: 2019

Type: review

Abstract: The infection caused by methicillin-resistant Staphylococcus aureus (MRSA) is a global threat to public health. Vancomycin remains one of the first-line drugs for the treatment of MRSA infections. However, S. aureus isolates with complete resistance to vancomycin have emerged in recent years. Vancomycin-resistant S. aureus (VRSA) is mediated by a vanA gene cluster, which is transferred from vancomycin-resistant enterococcus. Since the first VRSA isolate was recovered from Michigan, USA in 2002, 52 VRSA strains have been isolated worldwide. In this paper, we review the latest progresses in VRSA, highlighting its resistance mechanism, characteristics of VRSA infections, as well as clinical treatments.

Source: Journal of Advanced Research

DOI: 10.1016/j.jare.2019.10.005

Authors: Yanguang Cong, Sijin Yang, Xiancai Rao

Institutions: Southwest Medical University, Affiliated Hospital of Southwest Medical University, Army Medical University

Language: English

Topic: Antimicrobial Resistance in Staphylococcus

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $650