The Causes of Kidney Allograft Failure: More Than Alloimmunity. A Viewpoint Article
Year: 2019
Type: review
Abstract: Kidney allograft failure is a serious condition, as it implies the need for reinitiation of dialysis with associated morbidity and mortality, reduced quality of life, and higher economic cost. Despite improvements in short-term survival of kidney allografts, this progress was not matched in long-term graft survival. In this viewpoint article, we summarize the available literature on the causes of kidney allograft failure, both early and late, both nonimmune and alloimmune, to gain better insight into the causes of graft failure. Such insight is necessary to better target therapies or take preventative measures that improve long-term outcome after kidney transplantation.
Source: Transplantation
Authors: Elisabet Van Loon, Jelle Bernards, Amaryllis H. Van Craenenbroeck, Maarten Naesens
Institutions: Universitair Ziekenhuis Leuven, KU Leuven
Language: English
Subfield: Transplantation
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Unraveling the role of BK polyomavirus variants and of cellular CMP kinase on viral pathogenicity and clearance in renal-transplant patients, G1816819802, Building a Precision Medicine Pipeline for Antibody-Mediated and Antibody-Independent Phenotypes of Microvascular Rejection After Kidney Transplantation, Clinical use of non-invasive diagnostic biomarkers for antibody-mediated rejection and integration in the risk assessment pipeline for renal transplantation management., Biomarkers of renal graft injuries in kidney allograft recipients, G8481747230
OpenAlex ID: W2980320585