Work

In vitro antiproliferative studies of extracts of the marine molluscs: Tympanatonus fuscatus Var radula (linnaeus) and Pachymelania aurita (muller).

Year: 2019

Type: article

Abstract: = 0.52 ± 0.36 μg/ml) and also had the highest selectivity index of 4.94, 7.78 and 921.97 for DU145, HCC 1395 and Hep-2 cells respectively. Furthermore, TFAC was the only extract that significantly upregulated the expression of caspase 3, caspase 8 and P53. Thus, these findings suggest potential exploitation of TFAC as an anticancer agent.

Source: PubMed

Authors: Queensley Eghianruwa, Omolaja Osoniyi, Sabina Wachira, Naomi Maina, Regina Mbugua, Mabel Imbuga

Institutions: Adekunle Ajasin University, Obafemi Awolowo University, Kenya Medical Research Institute, Jomo Kenyatta University of Agriculture and Technology

Language: English

Topic: Marine Sponges and Natural Products

Subfield: Biotechnology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2980596737

FWCI: 1.067

Cites: 18

Cited by: 11

Related to: 10