Work

microRNA-758 inhibits the malignant phenotype of osteosarcoma cells by directly targeting HMGA1 and deactivating the Wnt/β-catenin pathway.

Year: 2019

Type: article

Abstract: and regulating the Wnt/β-catenin pathway. These results will aid in elucidating the roles of miR-758 and suggest that the miR-758/HMGA1/Wnt/β-catenin pathway represents a potential therapeutic target in OS.

Source: Europe PMC (PubMed Central)

Authors: Jia Ren, Mengjie Yang, Fengyang Xu, Juwu Chen

Institutions: First Affiliated Hospital of Zhengzhou University, Chinese Center For Disease Control and Prevention, National Institute for Viral Disease Control and Prevention

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2980756324

FWCI: 1.43

Cites: 37

Cited by: 20

Related to: 10