Work

Should we shift the paradigm of preclinical models for ARDS therapies?

Year: 2019

Type: editorial

Abstract: A 10.8-year-old, spayed female toy poodle presented with an esophageal foreign body. The foreign body was removed endoscopically, and a gastrostomy tube was placed to provide nutritional support during esophageal healing. The gastrostomy tube was later removed by endoscopic retrieval of the bulb through the esophagus. Immediately afterward, the dog developed hemothorax and eventually died. It was determined that many small arterial branches were avulsed from the aorta. The involved sections of aorta histopathogically evidenced medial necrosis, which was believed to be related to a prior disruption of blood flow through the vasa vasorum.

Source: Thorax

DOI: 10.1136/thoraxjnl-2019-213729

Authors: William Bain, Gustavo Matute-Bello

Institutions: University of Pittsburgh, University of Washington, VA Puget Sound Health Care System, Veterans Administration

Language: English

Topic: Respiratory Support and Mechanisms

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Veterans Affairs, Medical Research Council, National Heart, Lung, and Blood Institute