Association between PM2.5 exposure and peak expiratory flow rate in schoolchildren: a panel study
Year: 2019
Type: conference-abstract
Abstract: TPS 683: Short-term health effects of air pollutants 2, Exhibition Hall, Ground floor, August 28, 2019, 3:00 PM - 4:30 PM Background: PM2.5 exposure is known to have adverse effect on respiratory function in children. However, most of the previous studies were based on the ecological evaluation of outdoor exposure. The aim of the present study is to examine the association between individually monitored PM2.5 concentration and peak expiratory flow rate (PEFR). Methods: We recruited fifty-two 9-year-old children to conduct a panel study. Each child’s PM2.5 exposure was measured using indoor air quality monitor equipped with light-scattering particle sensor. The indoor air quality monitors were installed at the children’s classrooms and each child’s bedroom at their homes. We calculated daily mean concentration for each child according to the time spent at each place. PEFR was measured in 3 waves using peak expiratory flow meter at their class rooms (during week days) and homes (during weekend) between 8 and 9 AM through March to November 2018. Each wave was consisted of 7 consecutive days. We measured the children’s heights and weights to calculate the body mass index (BMI), and a questionnaire was administered to obtain information on covariates. We constructed a linear mixed model to examine the association adjusting for age, sex, BMI, environmental tobacco smoke exposure, housing type, previous history of asthma and allergic rhinitis, and monthly average household income. Result: A total of 784 observations were included in the present analysis. The mean daily PM2.5 concentration was 33.7±13.16 μg/m3 and ranged between 11.2 and 99.78 μg/m3. The mean PEFR was 285.3±51.52 L/min. The regression coefficient of PEFR (L/min) for the increment of 10 μg/m3 of daily mean concentration of PM2.5 was -3.73 (SE: 0.75, P-value<0.0001). Conclusion: We observed a statistically significant adverse association between individually monitored PM2.5 concentration and PEFR in 9-year-old children.
Source: Environmental Epidemiology
Language: English
Subfield: Health, Toxicology and Mutagenesis
Field: Environmental Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,200
OpenAlex ID: W2981702766