Elevated glutamate, glutamine and GABA levels and reduced taurine level in a schizophrenia model using an in vitro proton nuclear magnetic resonance method.
Year: 2019
Type: article
Abstract: H-NMR) method. In the MAM-treated rats, glutamate was increased in the thalamus and hypothalamus, glutamine was increased in the hippocampus and GABA was increased in the hippocampus and prefrontal cortex, while taurine showed a decrease in the striatum, temporal cortex and parietal cortex. These abnormalities may be helped further understanding the pathophysiology of schizophrenia.
Source: PubMed Central
Institutions: Chinese Academy of Sciences, Wuhan Institute of Physics and Mathematics, First Hospital of China Medical University, University of Chinese Academy of Sciences, Center for Excellence in Brain Science and Intelligence Technology, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, University of West London, China Medical University
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2981898527