Work

The ‘Omics Revolution: How an Obsession with Compiling Lists Is Threatening the Ancient Art of Experimental Design

Year: 2019

Type: article

Abstract: The last quarter of a century ushered in a transformation in Biology following the huge successes in sequencing entire genomes of organisms (including humans) with increasing precision and speed and rapidly decreasing cost: genomics.Later other "omics" approaches followed: proteomics, metabolomics, epigenomics, and many more.Huge quantities of data were generated and new computational methods to find hidden correlations emerged.Almost imperceptibly, however, it seems that this has led to a crisis in our ability to design elegant experiments to establish causality.

Source: BioEssays

DOI: 10.1002/bies.201900168

Author: Claudio D. Stern

Institution: University College London

Language: English

Topic: Philosophy and History of Science

Subfield: History and Philosophy of Science

Field: Arts and Humanities

Domain: Social Sciences

Open Access status: green

Funders: Wellcome Trust, British Heart Foundation, Biotechnology and Biological Sciences Research Council

Awards: Deconstructing and reconstructing heart development. ,, Organizers: orchestrators of developmental decisions, G6937337138