Work

GDNF-expressing macrophages restore motor functions at a severe late-stage, and produce long-term neuroprotective effects at an early-stage of Parkinson’s disease in transgenic Parkin Q311X(A) mice

Year: 2019

Type: article

Source: Journal of Controlled Release

DOI: 10.1016/j.jconrel.2019.10.027

Authors: Yuling Zhao, Matthew J. Haney, Yeon S. Jin, Olga Uvarov, Natasha Vinod, Yueh Z. Lee, Benjamin Langworthy, Jason P. Fine, Myosotys Rodriguez, Nazira El-Hage, Alexander V. Kabanov, Elena V. Batrakova

Institutions: University of North Carolina at Chapel Hill, Florida International University

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: North Carolina Biotechnology Center, Georgia Clinical and Translational Science Alliance, National Institutes of Health, National Institute of Neurological Disorders and Stroke, National Center for Advancing Translational Sciences, Eshelman Institute for Innovation, University of North Carolina at Chapel Hill, North Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill

Awards: G2118698080, G3864592560, G4163160421, Cell-based Platform for Gene Delivery to the Brain, North Carolina Translational and Clinical Science Institute (NC TraCS), G7017814389, Extracellular Vesicles for CNS Delivery of Therapeutic Enzymes to Treat Lysosomal Storage Disorders, G8066218739

OpenAlex ID: W2982637385

FWCI: 2.426

Cites: 55

Cited by: 47

Related to: 10