Work

Author response: A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation

Year: 2017

Type: peer-review

Abstract: A novel lncRNA (Ephemeron) is connected to known post-transcriptional and epigenetic regulators as part of an integrated machinery, which controls the timely exit from the naïve state of mouse embryonic stem cells.

DOI: 10.7554/elife.23468.032

Authors: Meng Amy Li, Paulo P Amaral, Priscilla Cheung, Jan H Bergmann, Masaki Kinoshita, Tüzer Kalkan, Meryem Ralser, Sam Robson, Ferdinand von Meyenn, Maike Paramor, Fengtang Yang, Caifu Chen, Jennifer Nichols, David L Spector, Tony Kouzarides, Lin He, Austin Smith

Institutions: Wellcome/MRC Cambridge Stem Cell Institute, University of Cambridge, Wellcome Trust, Medical Research Council, University of California, Berkeley, The Gurdon Institute, Cold Spring Harbor Laboratory, Babraham Institute, Wellcome Sanger Institute, Integrated DNA Technologies (United States)

Language: English

Topic: Pluripotent Stem Cells Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W2982735790

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