Work

The Use of Volatile Anesthetics as Sedatives for Acute Respiratory Distress Syndrome

Year: 2019

Type: article

Abstract: Acute respiratory distress syndrome (ARDS) remains to pose a high morbidity and mortality without any targeted therapies. Sedation, usually given intravenously, is an important part of clinical practice in intensive care unit (ICU), and the effect of sedatives on patients' outcomes has been studied intensively. Although volatile anesthetics are not routine sedatives in ICU, preclinical and clinical studies suggested their potential benefit in pulmonary pathophysiology. This review will summarize the current knowledge of ARDS and the role of volatile anesthetic sedation in this setting from both clinical and mechanistic standpoints. In addition, we will review the infrastructure to use volatile anesthetics.

Source: Translational Perioperative and Pain Medicine

DOI: 10.31480/2330-4871/084

Authors: Koutsogiannaki Sophia, MotomuShimaoka, Yuki Koichi

Institutions: Boston Children's Hospital, Harvard University, Mie University

Language: English

Topic: Respiratory Support and Mechanisms

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Institute of General Medical Sciences