Year: 2019
Type: article
Abstract: The cannabis plantThe cannabis plant is a term that groups the genus Cannabis, which comprises the Cannabis Sativa, Cannabis Indica, Cannabis Americana and Cannabis ruderalis plants.In general, cannabis is known as marijuana and has at least a bit more than 100 different synonyms; Table 1 presents some. 1 Worldwide prevalence of marijuana consumption is estimated to be 3.8 %, which means there are approximately 183.3 million users.One of the central problems is the consumption of marijuana by individuals under AbstractThe interest on cannabinoids became evident between the 1940 and 1950 decades.Although the active substance of the plant was not known, a series of compounds with cannabinomimetic activity were synthesized, which were investigated in animals and clinically.The most widely tested was Δ6α, 10α-THC hexyl.Δ6α, 10α-THC dimethylheptyl (DMHP) antiepileptic effects were studied in several children, with positive results being obtained in some cases.DMHP differs from sinhexyl in that its side chain is DMHP instead of n-hexyl.The first cannabinoid isolated from Cannabis sativa was cannabinol, although its structure was correctly characterized several years later.Cannabidiol was isolated some years later and was subsequently characterized by Mechoulam and Shvo.In 2013, the National Academy of Medicine and the Faculty of Medicine of the National Autonomous University of Mexico, through the Seminar of Studies on Entirety, decided to carry out a systematic review on a subject that is both complex and controversial: the relationship between marijuana and health.In recent years, studies have been conducted with cannabis in several diseases: controlled clinical trials on spasticity in multiple sclerosis and spinal cord injury, chronic, essentially neuropathic, pain, movement disorders (Gilles de Latourette, dystonia, levodopa dyskinesia), asthma and glaucoma, as well as non-controlled clinical trials on Alzheimer's disease, neuroprotection, intractable hiccups, epilepsy, alcohol and opioid dependence and inflammatory processes.
Source: Gaceta Médica de México
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2983394630