Work

Author response: Cystic fibrosis drug ivacaftor stimulates CFTR channels at picomolar concentrations

Year: 2019

Type: peer-review

Abstract: Aqueous solubility of cystic fibrosis drug ivacaftor is ~200-fold lower, whereas the potency of its stimulatory effect on the CFTR channel is >100-fold higher, than reported, and is fully reversible.

Source: eLife

DOI: 10.7554/elife.46450.013

Authors: László Csanády, Beáta Töröcsik

Institution: Semmelweis University

Language: English

Topic: Cystic Fibrosis Research Advances

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W2983496901

Cites:

Cited by:

Related to: 10