Work

Haploinsufficient tumor suppressor genes.

Year: 2017

Type: article

Abstract: mutation in pancreatic ductal adenocarcinomagenesis, demonstrating the synergism of haploinsufficient TSGs and other oncogenic events. These TSGs can be targets for activation therapy in cancer since they retain a functional allele even in tumor cells.

Source: PubMed

Authors: Kazushi Inoue, Elizabeth A Fry

Institution: Wake Forest University Health Sciences

Language: English

Topic: Cancer-related Molecular Pathways

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute

Award: Dmp1-p53/YY1 interplays and their roles in lung cancer development