ROCK inhibitor Y-27632 maintains the propagation and characteristics of hair follicle stem cells.
Year: 2018
Type: article
Abstract: 6 weeks after their intracutaneous injection into immune-deficient mice. These findings suggest that Y-27632 maintains the self-renewal and stemness characteristics of HFSCs during primary skin tissue culture followed by enrichment passaging and that HFSCs derived with Y-27632 possess the differentiation potentials important for tissue engineering and other clinical applications.
Source: Europe PMC (PubMed Central)
Authors: Liyou An, Pingping Ling, Jing Cui, Jiqiang Wang, Xiumei Zhu, Jiao Liu, Yujian Dai, Yanhong Liu, Lan Yang, Fuliang Du
Institution: Nanjing Normal University
Language: English
Topic: Hair Growth and Disorders
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2984179331