Fatigue in rheumatoid arthritis: time for a conceptual model
Year: 2010
Type: editorial
Abstract: An under-acknowledged patient concern requires a new approach In recent years, formal collaboration with RA patients has explored what treatment outcomes are important to them. Patients repeatedly raise concerns about the major impact of RA fatigue. Qualitative research, replicated internationally, shows that patients with RA experience fatigue as uncontrollable and overwhelming yet find it largely ignored by clinicians [1]. Fatigue is highly prevalent in RA (up to 70% of patients), is as severe and frequent as pain [2] and is consistently prioritized by patients within their top outcome priorities, often as high or higher than pain [3]. Fatigue data also provide information about disease activity that is additional to that measured by the current ACR core set variables [4]. All these findings led to an international consensus at OMERACT in 2006 that fatigue should be measured in all clinical trials in addition to the core set [4]. Fatigue measurement is now recommended for other core data sets in Europe [RA Impact of Disease (RAID)], the UK [RA Patient Priorities for Pharmacological Interventions (RAPP-PI)] and the USA (ACR/EULAR recommendation for assessing remission).
Source: Rheumatology
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2138323507