Work

Effects of Non-PharmacologicalTreatments on Quality of Life in Parkinson’s Disease: A Review

Year: 2017

Type: article

Abstract: A Reviewto their low profile of adverse events [10].However, it is unclear how these non-pharmacological interventions affect QOL in PD.Hence, the purpose of this review was to analyze the state-of-the-science on the effects of non-pharmacological interventions on QOL in persons with PD.Since the last review of QOL in persons with PD was conducted in 2012 [11], this review fills the gap with updated and new evidence. MethodsThe literature search was conducted in 5 steps.First, electronic databases of PubMed, CINHAL, and PsycINFO were searched from the beginning dates of each database to September 1, 2016 by using keywords matched to medical subject headings: "Parkinson's disease/ therapy" and "QOL".Second, articles were excluded using keywords matched to medical subject headings: "drug therapy", "prescription drugs" and "deep brain stimulation".Two hundred and forty five articles were generated.Third, the study titles and abstracts were reviewed using the following inclusion criteria: 1) publication in English; 2) QOL assessed as an outcome; and 3) randomized control trial (RCT), experimental, or quasi-experimental design.Forth, studies meeting the inclusion criteria were screened out if they met at least one of the exclusion criteria: 1) surgical intervention; and 2) case study.If the abstract of a study did not provide enough information to determine its eligibility, the full article was reviewed.Lastly, we cross-searched the references of the selected studies from database search and identified 14 additional studies.Of the total 259 studies identified, 26 met the eligibility criteria and were included in this review (Figure 1).The matrix system by Garrard was used to summarize the eligible studies (Tables 1 and 2) [12].Each study was first rated for level of evidence: Level I (RCT or experimental) or Level II (quasiexperimental).Next, three authors (SA, YC, and TB) independently assessed the quality of each study using the Effective Public Health

Source: Journal of Parkinson’s Disease and Alzheimer’s Disease

DOI: 10.13188/2376-922x.1000021

Authors: Sangwoo Ahn, Yan Chen, Tim Bredow, Corjena Cheung, Fang Yu

Institutions: University of Minnesota, Taihe Hospital, Bethel University

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Institute on Aging