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Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-Like Receptors 7 and 8

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Year: 2019
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01201
Authors: Rosaura Padilla-Salinas, Rachel Anderson, Kentaro Sakaniwa, Shuting Zhang, Patrick Nordeen, Chuanjun Lu, Toshiyuki Shimizu, Hang Yin
Institutions: University of Colorado Boulder, The University of Tokyo, Peking University, Tsinghua University
Language: English

Topic: Immune Response and Inflammation
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Ministry of Science and Technology of the People's Republic of China, Japan Society for the Promotion of Science
Awards: 構造生物学的手法を用いた、自然免疫受容体TLRのシグナル伝達機構の解明, G5211243292, 运用特异性多肽探针研究跨膜蛋白-蛋白相互作用, G8608118393, Elucidation of molecular motion and new regulation mechanisms in innate immune sensors
OpenAlex ID: W2986477867
FWCI: 1.396
Cites: 55
Cited by: 21
Related to: 10
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