Therapeutic Potential of α- and β-Pinene: A Miracle Gift of Nature
Year: 2019
Type: review
Abstract: α- and β-pinene are well-known representatives of the monoterpenes group, and are found in many plants’ essential oils. A wide range of pharmacological activities have been reported, including antibiotic resistance modulation, anticoagulant, antitumor, antimicrobial, antimalarial, antioxidant, anti-inflammatory, anti-Leishmania, and analgesic effects. This article aims to summarize the most prominent effects of α- and β-pinene, namely their cytogenetic, gastroprotective, anxiolytic, cytoprotective, anticonvulsant, and neuroprotective effects, as well as their effects against H2O2-stimulated oxidative stress, pancreatitis, stress-stimulated hyperthermia, and pulpal pain. Finally, we will also discuss the bioavailability, administration, as well as their biological activity and clinical applications.
Source: Biomolecules
DOI: 10.3390/biom9110738
Institutions: Bam University of Medical Sciences, G.B. Pant Institute of Himalayan Environment and Development, Gazi University, RMIT University, Tajik State Medical University, Shahid Beheshti University, Shahid Beheshti University of Medical Sciences, Universidade do Porto, i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Queen Elizabeth Hospital, Zabol University of Medical Sciences
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,216
OpenAlex ID: W2986766321