Work

Author response: Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence

Year: 2016

Type: peer-review

Abstract: Stromal cell levels and localization of active α5β1-integrin are regulated by desmoplastic extracellular matrix control of αvβ5-integrin signaling, and predict clinical outcomes for pancreatic and renal cancer patients.

DOI: 10.7554/elife.20600.061

Authors: Janusz Franco-Barraza, Ralph Francescone, Tiffany Luong, Neelima Shah, Raj Madhani, Gil Cukierman, Essel Dulaimi, Karthik Devarajan, Brian L Egleston, Emmanuelle Nicolas, R Katherine Alpaugh, Ruchi Malik, Robert G Uzzo, John P Hoffman, Erica A Golemis, Edna Cukierman

Institution: Fox Chase Cancer Center

Language: English

Topic: Cell Adhesion Molecules Research

Subfield: Immunology and Allergy

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W2988043292

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