Work

Author response: Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity

Year: 2019

Type: peer-review

Abstract: Sox2 transcription is not correlated with spatial proximity of its essential regulatory enhancer in embryonic stem cells, suggesting gene transcription is not limited to periods of direct enhancer-promoter contact.

DOI: 10.7554/elife.41769.054

Authors: Jeffrey M Alexander, Juan Guan, Bingkun Li, Lenka Maliskova, Michael Song, Yin Shen, Bo Huang, Stavros Lomvardas, Orion D Weiner

Institutions: University of California, San Francisco, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W2988133418

Cites:

Cited by: 4

Related to: 10