Work

A challenging diagnosis of penile sarcomatoid squamous cell carcinoma

Year: 2019

Type: article

Abstract: We report a patient with penile sarcomatoid squamous cell carcinoma (SCC) initially misdiagnosed as condyloma acuminatum. Sarcomatoid SCC is a rare, aggressive, biphasic cancer that often presents a diagnostic challenge and carries a poor prognosis, especially after a delay in diagnosis. Although sarcomatoid SCC may exhibit a broad range of clinical features, the expression of p63 and keratin 34?E12 is a common finding. Our case highlights the importance of accurate clinicopathologic correlation to facilitate a timely diagnosis and management of this rare and highly aggressive malignancy.

Source: Dermatology Online Journal

DOI: 10.5070/d32510045818

Authors: Sophia Zhang, Hasan Khosravi, Michael Cardis, Jaroslaw Jedrych, Jonhan Ho, Yuri Bunimovich

Institutions: University of Pittsburgh, University of Pittsburgh Medical Center, UPMC Hillman Cancer Center

Language: English

Topic: Genital Health and Disease

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $300