Work

Author response: Fusion surface structure, function, and dynamics of gamete fusogen HAP2

Year: 2018

Type: peer-review

Abstract: Structure, dynamics, and mutation of a gamete fusion protein and comparisons to viral homologues suggest that after trimerization the domain bearing the membrane-inserting fusion loops can pivot with respect to the trimer 3-fold axis.

DOI: 10.7554/elife.39772.022

Authors: Juan Feng, Xianchi Dong, Jennifer Pinello, Jun Zhang, Chafen Lu, Roxana E Iacob, John R Engen, William J Snell, Timothy A Springer

Institutions: Boston Children's Hospital, Harvard University, University of Maryland, College Park, Northeastern University

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W2988588692

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